研究業績
私たちは、減量・代謝改善手術の改善メカニズムを解明すべく、臨床のみならず、基礎研究を行っています。
The Significance of Bile in the Biliopancreatic Limb on Metabolic Improvement After Duodenal-Jejunal Bypass. Kawana T, Imoto H, Tanaka N, Tsuchiya T, Yamamura A, Saijo F, Maekawa M, Tamahara T, Shimizu R, Nakagawa K, Ohnuma S, Kamei T, Unno M.Obes Surg. 2024 Mar 21. doi: 10.1007/s11695-024-07176-7.
The role of bilio-pancreatic limb in nonalcoholic steatohepatitis improvement after duodenal-jejunal bypass in rats. Ichikawa H, Imoto H, Tanaka N, Fujishima F, Tsuchiya T, Watanabe K, Aoki T, Kohyama A, Morikawa T, Ohnuma S, Naitoh T, Kamei T, Unno M.Surgery. 2021 Oct;170(4):1006-1013. doi: 10.1016/j.surg.2021.07.003.
Mechanism of Bile Acid Reabsorption in the Biliopancreatic Limb After Duodenal-Jejunal Bypass in Rats. Ueno T, Tanaka N, Imoto H, Maekawa M, Koyama A, Watanabe K, Motoi F, Kamei T, Unno M, Naitoh T. Obes Surg. 2020 Jul;30(7):2528-2537. doi: 10.1007/ s11695-020-04506-3.
Changes in Enterohepatic Circulation after Duodenal-Jejunal Bypass and Reabsorption of Bile Acids in the Bilio-Pancreatic Limb. Ise I, Tanaka N, Imoto H, Maekawa M, Koyama A, Watanabe K, Motoi F, Unno M, Naitoh T. Obes Surg. 2019 Jun;29(6):1901-1910. doi: 10.1007/s11695-019-03790-y.
Efficacy of Sleeve Gastrectomy with Duodenal-Jejunal Bypass for the Treatment of Obese Severe Diabetes Patients in Japan: a Retrospective Multicenter Study. Naitoh T, Kasama K, Seki Y, Ohta M, Oshiro T, Sasaki A, Miyazaki Y, Yamaguchi T, Hayashi H, Imoto H, Naoki T, Naitoh T. Obes Surg. 2018 Feb;28(2):497-505.
Increased Bile Acid Signals After Duodenal-Jejunal Bypass Improve Non-alcoholic Steatohepatitis (NASH) in a Rodent Model of Diet-Induced NASH. Tsuchiya T, Naitoh T, Nagao M, Naoki T, Watanabe K, Imoto H, Miyachi M, Motoi F, Unno M. Obes Surg. 2017 Dec;12. doi:10. 1007/s11695-017-3065-z.
Biliopancreatic limb plays an important role in metabolic improvement after duodenal-jejunal bypass in a rat model of diabetes. Miyachi T, Nagao M, Shibata C, Kitahara Y, Naoki T, Watanabe K, Tsuchiya T, Motoi F, Naitoh T, Unno M. Surgery. 2016 May;159(5):1360-71.
Effects of duodeno-jejunal bypass on glucose metabolism in obese rats with type 2 diabetes. Imoto H, Shibata C, Ikezawa F, Kikuchi D, Someya S, Miura K, Naitoh T, Unno M. Surgery Today. Feb;44(2):340-8, 2014
Effects of ileal interposition on glucose metabolism in obese rats with diabetes. Ikezawa F, Shibata C, Ikezawa F, Kikuchi D, Imoto H, Miura K, Naitoh T, Ogawa H, Sasaki I, Tsuchiya T. Surgery. 2012 Jun;151(6):822-30.
